Pharmacy Rorano Journal

Kadar Total Fenolik Ekstrak Etanol Jarak Pagar (Jatropha curcas. L) yang Berpotensi sebagai Antioksidan

2024-07-21T18:12:45+00:00

This study aims to determine the total phenolic content of Jatropha curcas leaf extract and evaluate its potential as an antioxidant. Fresh Jatropha curcas leaves were obtained from Ternate City and extracted using 96% ethanol through the maceration process. The total phenolic content in the extract was determined using the UV-Vis spectrophotometric method with the Folin-Ciocalteu reagent and gallic acid as the standard of comparison. The results showed that the ethanol extract of Jatropha leaves had a total phenolic content of 6,780 mg GAE/g. The resulting extract has thick characteristics, is green in color, and smells distinctive. The extraction yield of 19.46% shows the efficiency of the extraction method used. In conclusion, jatropha leaves contain high phenolic compounds, which support their potential as a source of natural antioxidants. This potential can be utilized in the development of health and pharmaceutical products, both in the form of traditional and modern medicines. This study provides valuable information related to the phenolic content of Jatropha leaves and supports its wider utilization in the health sector.

Uji Penetapan Total Flavanoid Ekstrak Etanol Jarak Pagar (Jatropha curcas. L) yang Berpotensi sebagai Antioksidan

2024-07-21T22:18:20+00:00

This study aims to determine the total flavonoid content in Jatropha curcas (L.) leaf extract. Fresh leaf samples were taken from Akeboca Village, Ternate, and extracted using ethanol. From 100 grams of samples extracted with 1000 mL of solvent, 18.41 grams of extract was obtained, resulting in a yield of 18.41%. Flavonoid content test was conducted using spectrophotometry with quercetin as the standard. The analysis showed that in 250 mg of extract, there was a flavonoid content of 13.459 mg QE/g, which is equivalent to 5.3836%. The conclusion of this study is that Jatropha leaf extract has a significant flavonoid content, showing potential as a source of antioxidant compounds useful for pharmaceutical and health applications. These results support the utilization of Jatropha leaves in the development of natural products with antioxidant activity.

Uji Aktivitas Antioksidan beberapa Fraksi Ekstrak Fuli Pala (Myristica fragrans Houtt) Dengan metode DPPH

2024-07-21T22:31:57+00:00

This study aims to evaluate the antioxidant activity of n-hexane fraction, chloroform fraction, and ethyl acetate fraction of Nutmeg (Myristica fragrans) mace extract using DPPH method. The results showed that the chloroform fraction had the highest antioxidant activity with an IC₅₀ value of 22.17, close to the effectiveness of Vitamin C which was used as a positive control with an IC₅₀ value of 18.60. The n-hexane fraction showed moderate antioxidant activity with an IC₅₀ value of 71.57, while the ethyl acetate fraction had the lowest activity with an IC₅₀ value of 129.89. This data suggests that the chloroform fraction of the nutmeg mace extract has the greatest potential as a natural antioxidant. The yield of the ethyl acetate fraction was the highest (40%), followed by the n-hexane fraction (38%) and chloroform fraction (10.8%). This study provides important insights into the effectiveness of various fractions of Mace extract in counteracting free radicals and opens up opportunities for therapeutic or nutraceutical applications. These findings support the use of nutmeg mace as a potential source of natural antioxidants, especially the chloroform fraction, in efforts to prevent oxidative stress-related diseases.